Table 6 The top-20 ranked AD candidate genes gathered by our method
Score | Gene | Description |
|---|---|---|
1477.54 | App | Amyloid beta (A4) precursor protein |
1469.69 | Apoe | Apolipoprotein E |
794.48 | Mapt | Microtubule-associated protein tau |
560.37 | Psen1 | Presenilin 1 |
150.82 | Bace1 | Beta-site APP cleaving enzyme 1 |
105.30 | Psen2 | Presenilin 2 |
66.48 | Snca | Synuclein, alpha (non A4 component of amyloid precursor) |
62.84 | Gsk3b | Glycogen synthase kinase 3 beta |
58.73 | Prnp | Prion protein |
52.96 | Bdnf | Brain-derived neurotrophic factor |
46.54 | Aplp2 | Amyloid beta (A4) precursor-like protein 2 |
45.49 | Serpine2 | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
43.20 | Mme | Membrane metallo-endopeptidase |
39.21 | Ide | Insulin degrading enzyme |
38.82 | Ncstn | Nicastrin |
37.61 | Cdk5 | Cyclin-dependent kinase 5 |
37.08 | Sorl1 | Sortilin-related receptor, LDLR class A repeats-containing |
36.96 | Ace | Angiotensin I converting enzyme |
35.06 | Apbb1 | Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
32.46 | Clu | Clusterin |