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Table 4 Detail breakdown of the seed sequence classification of 9 Pfam and 4 SMART domains with positive concordance rate of < 90%

From: On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation

Pfam/SMART domains

Domain length

Positive concordance/Total discordance

Total common hits

Orphaned hits HMMER2/3

Positive concordance (%)

Total discordance (%)

PF00433.19 Pkinase_C

159

108/89

197

55/0

54.82

45.18

PF01426.13 BAH

349

53/10

63

4/0

84.13

15.87

PF02098.11 His_binding

296

19/4

23

0/0

82.61

17.39

PF02965.12 Met_synt_B12

309

14/2

16

0/0

87.50

12.50

PF05594.9 Fil_haemagg

160

122/16

138

17/0

88.41

11.59

PF10590.4 PNPOx_C_seed

112

268/73

341

0/0

78.59

21.41

PF11736.3 DUF3299

235

79/13

92

0/0

85.87

14.13

PF13894.1 zf-C2H2_4

105

2/5

7

577/0

28.57

71.43

PF15612.1 WHIM1

66

29/4

33

3/0

87.88

12.12

SM00185 ARM

66

128/34

162

7/0

79.01

20.99

SM00304 HAMP

122

79/50

129

91/0

61.24

38.76

SM00320 WD40

119

580/137

717

1055/0

80.89

19.11

SM00733 Mterf

49

115/39

155

90/0

74.19

25.16