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Table 5 Top 5 predictions of each type for the 606 proteins without prior knowledge.

From: Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study

Type

Protein(ORF)

Prediction

UniProt

SGD

Correct

Q0045

mitochondrion

Mitochondrion inner membrane.

mitochondrion (IDA)

 

Q0080

mitochondrion

Mitochondrion membrane.

mitochondrion (IDA)

 

YAL020C

cytoplasm

 

cytoplasm (IDA, IPI)

 

YAL029C

bud

Bud.

cellular bud (IDA)

cellular bud tip (IDA)

 

YBL041W

cytoplasm;

nucleus

Cytoplasm.

Nucleus.

endoplasmic reticulum membrane (IC)

nucleus (IC)

Partial Correct

YAL042W

ER

Endoplasmic reticulum membrane;

Golgi apparatus membrane

ER to Golgi transport vesicle (IDA)

integral to endoplasmic reticulum membrane (IDA)

integral to Golgi membrane (IDA)

 

YBL088C

cytoplasm;

nucleus

Nucleus.

telomere

nucleus (IC)

mitochondrion (IDA)

 

YBR020W

cytoplasm;

nucleus

 

cytoplasm (IGI)

 

YBR072W

cytoplasm

 

cytoplasm (IDA)

nucleus (IDA)

 

YBR108W

actin;

cytoplasm

Membrane raft;

Peripheral membrane protein

actin cortical patch (IDA)

colocalizes-with membrane raft (IDA)

Mismatch

YAL003W

cytoplasm

 

ribosome (TAS)

 

YAL028W

cytoplasm;

nucleus

Endoplasmic reticulum membrane

endoplasmic reticulum (IDA)

 

YAL030W

lipid particle

Endomembrane system

cellular bud neck (IDA)

endosome (IDA)

plasma membrane (IDA)

trans-Golgi network (IDA)

transport vesicle (IDA)

 

YAL040C

cytoplasm

 

nucleus (IDA, IMP)

 

YAL062W

actin;

cytoplasm

 

nucleus (IDA)

mitochondrion (IDA)

Unknown

Q0120

 

Mitochondrion.

mitochondrion (IDA)

 

YAL034C

nucleus

  
 

YAR018C

spindle pole

  
 

YAR027W

 

Nucleus membrane;

Cell membrane

nuclear envelope (IDA)

 

YAR042W

 

Cytoplasm

Golgi apparatus membrane

Nucleus outer membrane

early endosome (IDA)

endoplasmic reticulum (IDA)

Golgi trans cisterna (IDA)

nuclear envelope (IDA)

  1. In this table, "UniProt" means the subcellular localization in general annotation (comments) in UniProt Database [25]. "SGD" means the cellular component of GO annotation in SGD database [26]. Each type corresponds to different situation of the match between our prediction and the experiment validation.