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Table 2 Protein co-localization for 28 experiment sources in the BioGRID database.

From: Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study

Experiment system Throughput technique number of interactions number of common l localizations
    ≥ 1 (reliability) ≥ 2
Affinity Capture-Luminescence low throughput 29 0.3448 0
Affnity Capture-MS high throughput 44399 0.5343 0.0798
  low throughput 5627 0.5873 0.0945
Affnity Capture-RNA high throughput 3657 0.2625 0.0014
  low throughput 86 0.3140 0.0581
Affinity Capture-Western high throughput 213 0.6526 0.0798
  low throughput 11257 0.5477 0.0759
Biochemical Activity high throughput 4211 0.3363 0.0686
  low throughout 3427 0.4471 0.1100
Co-crystal Structure low throughput 364 0.6593 0.1703
Co-fractionation high throughput 102 0.0098 0
  low throughput 585 0.4821 0.0598
Co-localization low throughput 448 0.5357 0.0588
Co-purification high throughput 11 0.8182 0.5455
  low throughput 1667 0.6155 0.0834
FRET high throughput 13 0.1538 0
  low throughput 121 0.6364 0.0579
Far Western low throughput 74 0.5811 0.0541
  high throughput 4738 0.4185 0.0319
PCA low throughput 409 0.5232 0.0098
  high throughput 9 0.3140 0
Protein-RNA low throughput 168 0.1116 0.0129
  high throughput 328 0.3333 0
Protein-peptide low throughput 233 0.4940 0.0833
  high throughput 27 0.5556 0.0370
Reconstructed Complex low throughput 3347 0.5088 0.0986
  high throughput 6624 0.3578 0.0773
Two-hybrid low throughput 4622 0.4799 0.1019