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Figure 10 | BMC Bioinformatics

Figure 10

From: Horizontal gene transfer dynamics and distribution of fitness effects during microbial in silico evolution

Figure 10

A population composed of cells evolved in partial A and B environments evolving in a combined XOR environment. (A) maximum fitness trajectory (wine) and number of divisions per epoch (grey); additional details for this evolutional trajectory are shown in the following panels: (B) HGT events with strong positive (increase in fitness Δw > +0.3) and very strong negative (decrease in fitness Δw < -0.4) fitness effects are shown with red and blue arrows, respectively; origins and heads of arrows represent fitness before and after HGT event, respectively; red arrow highlighted with the grey oval represents the HGT event, which resulted in the emergence of a fully evolved cell in this population (this event is described in detail in Fig. 4) (C) skewness and kurtosis of DFE for non-lethal mutation events calculated for every 50 epochs; (D) same as above, DFE of non-lethal HGT events; (E) frequency of lethal (deleterious) mutation and HGT events as a function of evolutionary time.

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