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Table 3 Bias and RMSE in brackets from 1000 simlated datasets (generated from new EMMIX-WIRE (EM-W) model with θ h 2 equal to 0.5 and d 2 equal to 0)

From: Clustering of time-course gene expression profiles using normal mixture models with autoregressive random effects

 

First component

Second component

Third component

Parameters

EM-W

Kim

EM-W

Kim

EM-W

Kim

p(0.585,

0.001

0.008

-0.001

-0.003

-0.001

-0.005

0.1,0.315)

(0.009)

(0.012)

(0.008)

(0.008)

(0.010)

(0.011)

a0(0.3,

0.001

0.008

-0.001

-0.018

0.003

-0.014

1,0.2)

(0.017)

(0.019)

(0.018)

(0.026)

(0.016)

(0.016)

a1(0.03,

-0.002

-0.023

-0.001

-0.005

0.003

-0.006

1,0.02)

(0.049)

(0.060)

(0.059)

(0.062)

(0.049)

(0.049)

b1(0.06,

-0.001

-0.014

0.016

0.019

0.002

0.004

0.9,0.01)

(0.026)

(0.031)

(0.033)

(0.038)

(0.032)

(0.033)

θ2(0.5,

0.071

1.162

0.081

1.158

0.078

1.159

0.5,0.5)

(0.081)

(1.162)

(0.119)

(1.160)

(0.090)

(1.159)

ρ(0.6

-0.032

-0.337

-0.037

-0.339

-0.036

-0.339

0.6,0.6)

(0.038)

(0.337)

(0.062)

(0.340)

(0.045)

(0.340)

σ2(1.0,

-0.059

 

-0.069

 

-0.064

 

1.0,1.0)

(0.068)

 

(0.106)

 

(0.077)

 

d2(0,

0

 

0.001

 

0.000

 

0,0)

(0.000)

 

(0.001)

 

(0.001)

 
 

EM-W

Kim

Proportion

 

Mean (RMSE) SD

Mean (RMSE) SD

(EM-W is better)

Error rate

0.078 (0.078) 0.008

0.081 (0.081) 0.009

738/1000

Rand

0.891 (0.110) 0.012

0.886 (0.115) 0.012

806/1000

Adjusted

0.780 (0.222) 0.023

0.769 (0.232) 0.025

802/1000