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Figure 8 | BMC Bioinformatics

Figure 8

From: TAPDANCE: An automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data

Figure 8

Genome-wide association of phenotypes and CISs. A) Genome-wide map of CISs calculated using all tumors, colon tumors or liver tumors. The –log base 10 of the CISs p-value is plotted with an upper threshold of 16. B)Heat map of CISs with p-value > 10-5 calculated using all tumors. The header bar indicates colon tumors in dark grey and liver tumors in light grey. Transposon insertions in CIS regions within a given library are indicated by red boxes in the first panel. In the second panel the Fisher’s exact test p-value has been converted to the –log base 10 is plotted as a heatmap with increasing yellow intensity showing increased statistical significance. The CIS containing the Apc gene is highly significantly associated with colon tumors, while a CIS containing the Egfr gene is highly associated with the liver tumors. Actual p-values for association are provided in Additional file 1: Table S6.

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BMC Bioinformatics

ISSN: 1471-2105

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