Figure 7

Comparison of EMIM and LEM for Case/Parent Trios. Plots showing the comparison of EMIM and LEM using simulated data for 4000 case/parent trios, assuming R₁=1.5 and R₂=2.25 at SNP number 1004 and S₁=2 and S₂=3 at SNP number 6004. Plots of the $-\underset{10}{log}$ p-values for each SNP to detect maternal effects given child and imprinting effects by: A: EMIM and B: LEM. Plots of the $log$ parameters values for: C: R₁; D: R₂; E: S₁; F: S₂; G: I _m . H: Plot of the $-\underset{10}{log}$ p-values for the alternative (5-parameter) model versus the null (3-parameter) model calculated using EMIM and MENDEL.