Table 10 Toxicity analysis result by using Lazar.
Ligand | Mutagenicity | Carcinogenicity | |||
|---|---|---|---|---|---|
| Â | Salmonella typhimurium (CPDB) | Salmonella typhimurium (Kazius/Bursi) | Rodent ( multiple sex ) | Rat ( both sex ) | Mouse ( both sex ) |
SAHA | no | no | no | no | yes |
1a | no | no | no | no | no |
1b | no | no | no | no | yes |
1c | no | no | no | no | no |
1d | no | no | no | no | no |
1e | no | no | yes | no | no |
1f | no | no | no | no | no |
2a | no | no | no | no | yes |
2b | no | no | no | no | yes |
2c | no | no | no | no | yes |
2d | no | no | no | no | yes |
2e | no | no | no | no | yes |
2f | no | no | no | no | yes |