Near-membrane ensemble elongation in the proline-rich LRP6 intracellular domain may explain the mysterious initiation of the Wnt signaling pathway

Table 4 T-test results on the constructed 100mer peptide.

t test
Alternative hypothesis: True difference in means is less than 0, i.e. the mean of undocking conformers’ Rgyr or end-to-end distance is less than that of docking conformers
	Mean of undocking conformers	Mean of docking conformers	p-value
Rgyr	28.4383	31.4704	<2.2e-16
D1-40	40.0255	41.8216	<2.2e-16
D31-70	43.6516	48.8396	<2.2e-16
D61-100	40.2149	41.3728	1.032e-14

The table shows t-test results on the Rgyr distributions and end-to-end distance distributions of docking and undocking structural ensembles of the constructed 100mer peptide.

ISSN: 1471-2105