Table 3 Fischer’s randomization test results of the pharmacophore hypothesis Hypo 1.
Validation no. | Total cost | Fixed cost | RMSD | Correlation |
|---|---|---|---|---|
Original hypothesis | ||||
Hypo1 | 81.24 | 74.770 | 0.804 | 0.977 |
Randomization results | ||||
Trial1 | 116.69 | 66.395 | 2.232 | 0.811 |
Trial2 | 133.35 | 69.600 | 2.496 | 0.756 |
Trial3 | 124.05 | 68.126 | 2.372 | 0.783 |
Trial4 | 189.35 | 62.993 | 3.500 | 0.397 |
Trial5 | 171.63 | 68.169 | 3.211 | 0.539 |
Trial6 | 158.05 | 63.578 | 3.074 | 0.591 |
Trial7 | 116.78 | 64.678 | 2.191 | 0.821 |
Trial8 | 135.62 | 68.457 | 2.580 | 0.736 |
Trial9 | 140.83 | 69.702 | 2.667 | 0.714 |
Trial10 | 172.23 | 64.740 | 3.257 | 0.520 |