Figure 2

Refinement of predictive power by additional filtering in the LT2 internal model. 'SVM(ALL)' represents the distribution of true positive counts as a function of the count of predictions for top-50 ranking in SVM portion of the analysis. The true positive count of 'SVM+Filtering' was re-estimated for prediction ranking after simple-criteria-based filtering. The true positive count for the respective total prediction count was the average of 10 randomly selected validation sets.