Table 1 Comparison of Estimates for Null Parameters (δ = -1, σ = 1, p0 = 0.909; 100 simulations).
From: Analyzing 2D gel images using a two-component empirical bayes model
50 bins, N= 550 | 100 bins, N= 550 | 100 bins, N= 5500 | ||||
|---|---|---|---|---|---|---|
mean, SD | unconstrained | constrained | unconstrained | constrained | unconstrained | constrained |
δ | -1.008 | -1.001 | -1.002 | -0.995 | -0.999 | -1.000 |
SD | 0.089 | 0.056 | 0.097 | 0.058 | 0.032 | 0.020 |
σ | 0.997 | 0.992 | 1.000 | 0.991 | 1.004 | 0.994 |
SD | 0.164 | 0.043 | 0.125 | 0.043 | 0.045 | 0.017 |
p 0 | 0.914 | 0.905 | 0.916 | 0.906 | 0.913 | 0.907 |
SD | 0.108 | 0.011 | 0.076 | 0.012 | 0.025 | 0.005 |