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Table 2 Energy functions for dangling bases

From: Lost in folding space? Comparing four variants of the thermodynamic model for RNA secondary structure prediction

Function

Description

dl _energy

A single base left of a closed substructure can dangle onto this stack and thus might further stabilize it.

dr _energy

Symmetric case to dl _energy.

ext _mismatch _energy

Two bases left and right of a stack, which do not form a basepair (they mismatch), can dangle from both sides to the stack.

dli _energy

A multiloop is closed by one stack. A single base at the inside of the multiloop and directly next to the closing stack might dangle from left onto this stack. The energy values are the same as dr _energy, but for a reversed subsequence.

dlr _energy

Symmetric case to dli _energy.

ml _mismatch _energy

Two bases on both inner sides of a multiloop closing stack may dangle from inside onto this stack, but do not form a basepair (mismatch).