Table 5 The effect of quality score modeling on quantification accuracy
From: RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Simulation model | Estimation model | MPE | 10% EF | FP |
|---|---|---|---|---|
theoretical | quality | 3.1/4.1/7.2 | 13.8/25.2/43.5 | 1.0/1.8/11.6 |
theoretical | profile | 3.1/4.1/7.2 | 13.9/25.3/43.6 | 1.0/1.8/11.7 |
empirical | quality | 3.1/4.0/7.0 | 14.2/25.3/43.0 | 1.2/2.0/11.4 |
empirical | profile | 3.1/4.1/7.0 | 14.3/25.4/43.2 | 1.1/2.0/11.2 |