From: Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study
Features | Ranking values |
---|---|
# of non-H | 0.167148 |
# of 2-degree cyclic atoms | 0.118946 |
degree of cyclization | 0.100268 |
# of non-H polar bonds | 0.056622 |
# of rotatable bonds | 0.049770 |
# of carbons in cap fragments | 0.047428 |
# of cap fragments | 0.043447 |
# of 3-degree cyclic atoms | 0.040664 |
# of N and O atoms | 0.038882 |
# of H-bond acceptors | 0.038103 |
# of fragments | 0.033010 |
maximum cap fragment size | 0.032459 |
# of 2-degree acyclic atoms | 0.027549 |
# of 3-degree acyclic atoms | 0.021673 |
# of 3-level bonding patterns | 0.018798 |
total SSSR size | 0.017162 |
total number of 3-8 membered rings | 0.017162 |
# of cyclic fragments | 0.016538 |
# of 1-level bonding patterns | 0.016382 |
# of H-bond donors | 0.016217 |
total number of 3 to 8 unsaturated rings | 0.016072 |
# of aromatic systems | 0.014930 |
# of N with # of H > 0 | 0.012320 |
# of hydroxyl groups | 0.009301 |
maximum SSSR size | 0.008863 |
# of linkers | 0.008807 |
# of 2-level bonding patterns | 0.006729 |
total number of 3 to 8 saturated rings | 0.004750 |