Figure 1

Pathway regulation in Plasmodium infected human periphery blood. Each pathway was divided into two subpathways according to ortholog genes defined in Kyoto Encyclopedia of Genes and Genomes. Each box represents a pathway. The blue part denotes host-parasite ortholog genes constituted subpathway, which is named host-parasite common subpathway; the red part is constituted by host genes which have no ortholog in parasite, and is named host-specific subppathway. In each subpathway, the arrow indicates if the subpathway is significantly up- or down- regulated (p-value≤0.05 after bonferroni correction as significant; p-value≤0.1 after bonferroni correction provided to give more complete information on linked pathways/sub-pathways). We showed here the regulation pattern of pathways related to metabolism of fatty acid (KEGG ID hsa00061, hsa00062 and has00071) and pantothenate (KEGG ID hsa00770).