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Table 1 Gene ontology based tissue expression divergence.

From: Association of tissue lineage and gene expression: conservatively and differentially expressed genes define common and special functions of tissues

Tissue Node

Human (4207 GO modules)

Mouse (2321 GO modules)

Annotation

GO Distance

KS.test

Correlation

GO Distance

KS.test

Correlation

  

Zygote

2

18

93

2

3

94

pluripotent stem cell

Mesendoderm

0

32

101

1

12

102

endoderm & mesoderm

Endoderm

29

7

202

1

29

109

endoderm tissues

PrimitiveGut

20

14

228

3

26

122

primitive gut 1 & 2 & 3

PrimitiveGut3

92

98

884

64

78

535

thymus & prostate

PrimitiveGut2

47

244

297

7

124

115

pancreas & liver

PrimitiveGut1

116

13

558

180

4

1399

trachea & lung

Mesoderm

0

78

91

20

15

222

mesoderm tissues

ParaxialMesoderm

42

79

313

108

18

722

skin & skeletal muscle

IntermediateMesoderm

10

120

236

30

47

255

intermediate

KU

49

259

389

91

30

600

uterus & kidney

Gonad

35

239

429

33

228

235

testis & ovary

Ectoderm

22

14

273

111

0

703

ectoderm tissues

NeuralCrest

327

1

810

437

0

2106

neural crest

NeuralTube

233

0

827

241

0

1587

neural tube

Brain

201

3

795

216

0

1524

brain 1 & 2

Brain2

146

60

714

368

0

1728

cerebellum & olfactory bulb

Brain1

337

9

1292

224

0

1491

prefrontalcortex & amygdala & pituitary & hypothalamus

  1. The thresholds for these measurements are: GO Distance: p < 0.05 (or integrated p < 0.05); KS test: p < 0.05 (or integrated p < 0.05); Correlation: r > 0.9.