Table 1 Performance comparison between the three methods of catalytic residue prediction when evaluation was carried out by chain, family, superfamily and fold. Methods were evaluated on the same data set using 10-fold cross-validation. sn means the sensitivity when specificity is 0.95.
| Â | FEATURE | GBT | Structure Kernel | |||
|---|---|---|---|---|---|---|
| Â | AUC | sn | AUC | sn | AUC | sn |
Fold | 76.4 | 0.20 | 80.4 | 0.34 | 86.1 | 0.40 |
Superfamily | 76.5 | 0.20 | 80.8 | 0.34 | 86.1 | 0.40 |
Family | 76.7 | 0.21 | 80.7 | 0.34 | 86.8 | 0.42 |
Chain | 76.7 | 0.21 | 81.1 | 0.34 | 87.3 | 0.45 |