Figure 1From: Genome-wide sequence-based prediction of peripheral proteins using a novel semi-supervised learning techniqueAn example of the peripheral domain (C2-domain of PKCα, PDB ID: 1DSY). The protein targets specific lipids in the membranes in response to certain signal which, in this case, is binding of 2 Ca2+ ions (shown as red spheres). The protein (shown in cartoon representation) penetrates the membrane partially. Lipid hydrogens are not shown for clarity.Back to article page