Table 1 Statistics on added proteins across different databases
From: Extending pathways and processes using molecular interaction networks to analyse cancer genome data
Property | BioCarta | KEGG | Reactome |
|---|---|---|---|
no. of examined pathways | 322 | 199 | 79 |
no. of extended pathways | 195 | 140 | 62 |
avg. pathway size | 19 | 49 | 75 |
avg. size after extension | 24 | 61 | 85 |
total no. of added proteins | 935 | 1745 | 622 |
no. of unique added proteins | 280 | 623 | 409 |
Molecular function categories of proteins added by the extension method (2-fold enrichment, see methods) | Phosphatase activity, Regulator activity, Binding, Kinase inhibitor/regulator, Cytokine binding/TNF receptor | Phosphatase activity, Regulator activity, Cytokine binding/TNF receptor | Regulator activity |