Figure 4
From: Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers
The resulting power for two markers showing significance after BH adjustments. The power is calculated as the percentage of times the null hypothesis is rejected. To reach 90% power, Ndiff = 30 samples per group is required for ID:138036 (top), whereas for ID:19655 (bottom) Ndiff = 15 may be enough. From the original 134 samples, 30 cohorts of 2 × 7 subjects each were randomly built. From each cohort, 2000 resamples of increasing sample size (10-120) were generated via bootstrap with replacement. Circles indicate outliers.