Figure 2
From: IntelliGO: a new vector-based semantic similarity measure including annotation origin
Intra-set similarities with the KEGG pathway dataset using BP annotations. The intra-set similarity is calculated as the mean of all pairwise gene similarities within a KEGG pathway, with the four measures compared in this study, namely, IntelliGO (using EC weight List1 ), Lord-normalized, Al-Mubaid, and Weighted-cosine. A set of thirteen pathways were selected from the KEGG Pathway database for yeast (top panel) and human (bottom panel) pathways. Only BP annotations are used here (see also Table 2).