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Table 1 Performance comparison by samples selection by ΔASA

From: Sequence-based identification of interface residues by an integrative profile combining hydrophobic and evolutionary information

SVM

Sen

Spec

Acc

MCC

Prec

F1

ΔΔASA

1

24.18

98.31

77.85

0.3728

84.51

37.6

 

2

24.11

98.28

77.81

0.3712

84.27

37.5

 

3

23.87

98.19

77.67

0.3656

83.41

37.12

66.9Ã…2

4

24.62

98.48

78.09

0.3828

86.04

38 28

 

5

23.91

98.21

77.7

0.3666

83.57

37.18

 

6

20.75

97

75.95

0.2944

72.51

32.26

 

7

20.53

96.92

75.83

0.2892

71.75

31.92

 

8

20.49

96.9

75.81

0.2883

71.61

31.87

14.5Ã…2

9

21.02

97.1

76.1

0.3003

73.44

32.68

 

10**

20.42

96.87

75.77

0.2866

71.35

31.75

 

1***

44.58

91.52

78.56

0.4161

66.71

53.45

 

2

43.73

93.05

79.44

0.4367

70.59

54

 

3

43.03

94.4

80.21

0.4571

74.54

54.56

 

4

42.09

95.41

80.69

0.4703

77.77

54.62

 

5

39.76

96.91

81.14

0.4842

83.07

53.78

 

6

6.84

99.17

73.68

0.1726

75.88

12.55

 

7

6.16

99.39

73.66

0.1717

79.52

11.44

 

8

5.57

99.53

73.59

0.168

81.93

10.41

 

9

4.83

99.71

73.52

0.1646

86.37

9.15

 

10

4.28

99.82

73.45

0.1611

90.07

8.17

 
  1. *The subtraction between average ΔASA for positive samples and that for negative samples.
  2. **The above ten numbers from 1 to 10 stand for the ten-SVMs.
  3. ***The following ten ones stand for the combined SVMs with thresholds from 1 to 10.