Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster

BMC Bioinformatics

Table 5 Role of TFs in comparison with presence of SUMOylation consensus motif and the role reported in the literature.

	*Bcd*	*Cad*	Hb	*Tll*	Gt	Kr	*Kni*	*TorRE*
roles	s	+	s	-	s	s	-	s
Number of SUMO sites	1	0	2	0	1	2	0	1
Perkins et al. [29]	+	+	s	-	s	s	-	NA
Schroeder et al. [9]	+	+	s	-	-	(s)	-	+
Rivera-Pomar et al. [35]	+	+	s	-	-	s	-	NA
Sanchez et al. [36]	+	+	s	-	-	-	-	NA
Jaeger et al. [37]	+	+	s	-	s	s	s	NA

The first row indicates the role we assign to the TFs, where "+" indicate activators, "-" indicate repressors, and "s" indicates a TF switching roles. The second row shows the number of sites found in the protein sequence of the TF that match the SUMO-consensus motif. The last rows summarizes the roles for the TFs previously reported in the literature.

ISSN: 1471-2105