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Table 2 Table of 24 GO terms which were used to generate the ROC plot.

From: Integrating gene expression and GO classification for PCA by preclustering

GO term

description

GO:0007050

cell cycle arrest

GO:0009653

morphogenesis

GO:0001558

regulation of cell growth

GO:0045786

negative regulation of progression through cell cycle

GO:0016055

Wnt receptor signaling pathway

GO:0008284

positive regulation of cell proliferation

GO:0016049

cell growth

GO:0009790

embryonic development

GO:0007178

transmembrane receptor protein serine/threonine kinase signaling pathway

GO:0001501

skeletal development

GO:0000188

inactivation of MAPK activity

GO:0030111

regulation of Wnt receptor signaling pathway

GO:0045595

regulation of cell differentiation

GO:0001503

ossification

GO:0000187

activation of MAPK activity

GO:0000165

MAPKKK cascade

GO:0043406

positive regulation of MAPK activity

GO:0030198

extracellular matrix organization and biogenesis

GO:0050793

regulation of development

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0042127

regulation of cell proliferation

GO:0040007

growth

GO:0051216

cartilage development

GO:0000902

cellular morphogenesis

  1. The terms are present in the genes which were used to generate the mean pro les in the X matrix, before and after preclustering. The terms were selected by biologists and expected to be relevant to the biologic context of the experiment, which is the development of human mesenchymal stem cells to osteoblasts.