Figure 5From: Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100(a) Snapshots taken at the end of 20 ns simulation of Mc6A. W23 of p53 (red) is out of the binding pocket. (b) Snapshot taken at the end of 22 ns of the simulation of the trajectory Mc6A7ns, showing the crystallographically observed binding mode of the side chains F19, W23 and L26 and W23-L54 HB is formed.Back to article page