Gram A | Gram B | Frequency | P-value |
---|
LKEL | LKEL | 36 | 2.2 × 10–16 |
ELLK | ELLK | 35 | 7.7 × 10–16 |
LKKI | LKKI | 33 | 2.2 × 10–16 |
LKKL | LKKL | 32 | 2.2 × 10–16 |
LSKL | LSKL | 32 | 2.2 × 10–16 |
DLSK | DLSK | 31 | 2.2 × 10–16 |
ELLN | ELLN | 31 | 2.2 × 10–16 |
LKSL | LKSL | 31 | 2.2 × 10–16 |
EKLV | EKLV | 30 | 2.2 × 10–16 |
LKNL | LKNL | 30 | 2.2 × 10–16 |
- For clarity, only gram pairs whose number of occurrence is greater than 30 were listed. A full list of gram pairs passing the cut-off value (Number of hits: 8.3) is provided online as a supplementary table. P-values for gram pairs were calculated using z-test by comparing the actual frequency of each gram pair to its corresponding frequencies in 1000 randomized domain-domain interaction data sets.