Table 5 First- and second-order-neighbor subnetworks of Parkinson's disease data. The classification error, number of selected disease genes, number of selected genes, and their standard errors (SE in parentheses) were obtained by averaging over 10 runs. Eight disease genes were UBE1, PARK2, UBB, SEPT5, SNCAIP, GPR37, TH, and SNCA.
From: Network-based support vector machine for classification of microarray samples
Network | Method | Error | # Disease Genes | # Genes |
|---|---|---|---|---|
PD-1nb-net | STD | 0.476 (0.023) | 8.0 (0.0) | 16.0 (0.0) |
L1 | 0.471 (0.017) | 2.8 (0.7) | 6.1 (1.5) | |
New (w = 1) | 0.462 (0.016) | 3.4 (0.8) | 7.3 (1.7) | |
New (w = ) | 0.462 (0.014) | 3.6 (0.7) | 8.4 (1.5) | |
New (w = d) | 0.482 (0.015) | 3.0 (1.2) | 7.5 (2.1) | |
Final Model | - | 8.0 | 16.0 | |
PD-2nb-net | STD | 0.444 (0.016) | 8.0 (0.0) | 26.0 (0.0) |
L1 | 0.449 (0.017) | 3.1 (0.5) | 10.9 (2.1) | |
New (w = 1) | 0.464 (0.022) | 5.3 (0.9) | 13.2 (3.2) | |
New (w = ) | 0.447 (0.023) | 6.1 (0.8) | 13.7 (2.7) | |
New (w = d) | 0.433 (0.016) | 6.2 (0.9) | 20.0 (2.5) | |
Final Model | - | 8.0 | 26.0 |