From: GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
Tool | P-value and statistical method | Flexible threshold | Graphical visualization | Multiple organisms | Running time |
---|---|---|---|---|---|
GOrilla | Exact mHG p-value computation (no need for simulations) | + | + | + | 7 Sec |
Fatiscan [13] | Fischer Exact (FDR corrected for number of thresholds) | + (predetermined steps of 30) | - | + | 30 Min |
GO-stat [14] | Wilcoxon Rank-Sum/Kolmogorov Smirnov | + | - | + | 2 Min |
GOEAST [9] | Hypergeometric | - | + | + | 20 Min |
SGD [11] | Hypergeometric | - | + | - (only yeast) | 2 Min |
DAVID [7] | Modified Fischer Exact | - | - | + | 2 Min |
GOTM [10] | Hypergeometric | - | + | + | 2 Min |
GoMiner [3] | Fisher Exact | - | - (only in the downloadable version) | + | 7 Min |