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Table 2 Significant Splicing Events

From: Identifying differential exon splicing using linear models and correlation coefficients

Affymetrix Probeset ID

Gene and exon

LIMMA Comparison

Rank in analysis of unfiltered dataset (Benjamini-Hochberg-corrected p-value)

Rank with analysis of filtered dataset A (Benjamini-Hochberg-corrected p-value)

Rank with analysis of filtered dataset B (Benjamini-Hochberg-corrected p-value)

3400083

WNK1 exon 3

ENSE00000437674

Kidney vs. non-kidney

53

(1.7e-12)

11

(1.9e-12)

1

(7.0e-12)

3400090

WNK1 exon 4

ENSE00000711974

Kidney vs. non-kidney

82

(1.1e-11)

21

(1.5e-11)

4

(5.5e-11)

3400056

WNK1 exon 1

ENSE000001527902

Kidney vs. non-kidney

161

(1.3e-10)

44

(1.7e-10)

9

(5.5e-10)

3400080

WNK1 exon 2

ENSE00000711927

Kidney vs. non-kidney

507

(2.2e-08)

169

(3.3e-08)

35

(1.1e-07)

3427830

SLC25A3 exon3B

ENSE00000753648

Muscle vs. non-muscle

25

(5.9e-13)

3

(1.3e-12)

2

(1.2e-12)

3427830

SLC25A3 exon3B

ENSE00000753648

Heart vs. non-heart

106

(1.7e-11)

41

(1.1e-11)

8

(3.6e-11)

3427827

SLC25A3 exon 3A

ENSE00000753647

Heart vs. non-heart

236

(5.2e-10)

112

(5.8e-10)

26

(1,8e-09)

3427827

SLC25A3 exon 3A

ENSE00000753647

Muscle vs. non-muscle

263

(1.6e-09)

126

(1.7e-09)

35

(4.6e-09)

3427827

SLC25A3 exon 3A

ENSE00000753647

Thyroid vs. non-thyroid

308

(3.9e-07)

114

(1.2e-09)

22

(2.2e-06)

3918911

ITSN exon 40

ENSE00001488185

Cereb. vs. non-cereb

480

(1.6e-12)

225

(1.7e-12)

63

(4.4e-12)

3918909

ITSN exon 40

ENSE00001488185

Cereb. vs. non-cereb

1822

(1.7e-09)

873

(2.0e-09)

353

(3.6e-09)

3918908

ITSN exon 40

ENSE00001488185

Cereb. vs. non-cereb

1884

(2.1e-09)

885

(2.1e-09)

359

(3.8e-09)

3918903

ITSN exon 35

ENSE00001488224

Cereb. vs. non-cereb

2304

(6.6e-09)

1107

(7.2e-09)

466

(1.2e-08)

2562711

IMMT exon 6

ENSE00000768006

Heart vs. non-heart

37

(4.5e-13)

17

(3.7e-13)

1

(4.3e-12)

2319719

KIF1B exon 20

ENSE00001472763

Heart vs. non-heart

129

(3.6e-11)

55

(3.1e-11)

Not present in dataset B

2319721

KIF1B exon 20

ENSE00001472763

Heart vs. non-heart

134

(4.4e-11)

61

(4.2e-11)

Not present in dataset B

2319722

KIF1B exon 20

ENSE00001472763

Cereb. vs. non-cereb

486

(1.8e-12)

218

(1.7e-12)

Not present in dataset B

2319721

KIF1B exon 20

ENSE00001472763

Cereb. vs. non-cereb

1784

(1.4e-09)

830

(1.4e-09)

Not present in dataset B

  1. Table showing the effect of filtering on the ranking of real splice events. All the probesets in the table had a Benjamini-Hochberg-corrected p-value less than 0.0001 and for each there is literature evidence of the identified splicing events.