Results for the Estrogen gene signature. A screenshot of the sscMap program displaying the volcano plot for the Estrogen gene signature. The x-axis is for the standardized connection score, while the y-axis is for -log10 p. The green horizontal line is for the pre-set threshold p-value. Any data points above that line are considered as statistically significant. In the example shown in this figure, the threshold p-value was set as 1/N = 1/3738.