Figure 3From: The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genesThe Four p53 Correspondence Motifs. The four correspondence motifs for the repeated, palindromic p53 RE are graphically represented. In the top three motifs, each line corresponds 2 synonymous positions. In the bottom motif, the previously independent half-sites are made corresponding (tied) by the yellow connecting lines so that now 4 synonymous positions are corresponded. The completely un-tied motif (not shown) has no correspondence, and thus no connecting lines, between any of the positions in the motif. (R = A or G, W = A or T, and Y = C or T. Position ã has the complement nucleotide emission distribution of a.)Back to article page